THE SYNDROME OF ENDOGENOUS INTOXICATION IN PATIENTS WITH CANCER OF THE MAMMARY GLAND
06.05.2015
Rasulov S.R., Murodov А.М., Khamidov А.К., Ashurova M.J.
In the structure of the morbidity and mortality of the female population of cancer of the mammary gland takes the first place. The severity of manifestations of GIS in patients with cancer of the mammary gland caused by the passage of the disease (depending on the stage of the disease) and the applied method of special treatment: surgery, chemotherapy, radiation therapy. Study of biochemical markers of endogenous intoxication in patients with cancer of the mammary gland showed a decrease in total protein, albumin fraction and test the Paramecium, a slight increase in globulin, which testifies to the existence of the phenomena of intoxication depend on the stage of the prevalence of tumor process. In patients with cancer of the mammary gland, compared with healthy, have lower indicators of the quality of life, especially for the account of such scales as physical functioning and men-tal and emotional state.
СЛОВО ГЛАВНОГО РЕДАКТОРА
Наше издание является научно-практическим журналом, в котором публикуются основные научные результаты диссертаций на соискание ученой степени кандидата и/или доктора медицинских наук как нашего института, так и других лечебно-учебных медицинских учреждений, интересные случаи из практики, обзоры литературы, лекции и юбилейные статьи. Журнал выходит 4 раза в год, и каждый номер имеет не менее 80 страниц. Каждая поступающая статья принимается по требованиям, проходит строгий отбор и отдается для выпуска в номер только после рецензирования и обязательного редактирования.
У нас принято одностороннее слепое рецензирование. Рецензенты уделяют особое внимание содержанию статьи и проверке данных статистической обработки, их соответствие современным требованиям.
Главный редактор журнала доктор медицинских наук Мухиддинов Н. Д.-
Preventive maintenance and therapy of shortage of iron in an organism at pregnancy
Nurmatova Z.I., Nurmatov A.A., N.I. Ibragimov
Thus, the preparation of folic acid (folacini) can be recommended for wide application in practical public health services in female consultations, maternity hospitals for treatment of anemia’s at pregnant women and women in childbirth in the postnatal period, especially at transferred blood in тhe use and early postnatal the periods or at a Cesarean section. The given preparation is safe; simple in also does not demand additional service (the pregnant woman can easy accept itself).
It is not necessary to stop treatment by preparations of iron after normalization of level of hemoglobin and the maintenance earitrocitis in an organism. Normalization of level of hemoglobin in an organism does not mean restoration of stocks of iron in it. For this purpose experts the CART recommend after 2-3 the monthly treatments and liquidation hematology a picture of an anemia not to stop therapy carrying out, and only to reduce twice a dose of a preparation which was used for treatment against an anemia anemias. Such course of treatment proceeds within 3 months. Even having restored completely iron stocks in an organism expediently during half a year to accept small doses of ferriferous preparations.
Development of an anemia during pregnancy negatively influences a current development process and is the serious factor of braking after a birth adaptations.
Timely and adequate treatment, preventive application shortage of iron in an organism
Preparations from early terms hestacy – pledge of safe end of pregnancy both for mother, and for the newborn. -
Condition and methods of prevention at school and street accidents reading to disability (in Dushanbe, Tajikistan)
Mirzoeva Z.A., Hisomova H.K., Ortikova M.M.
The family doctor can show care, gain trust of children and their parents, attention and correctness in relation to patients. It has good knowledge and skills of questions to prevention of a school and street invalidation. The family doctor has a key to professional consultation. -
TREATMENT AND PREVENTION OF VIRAL INFECTIONS WITH THE USE OF INTERFERON INDUCTORS
MIRZOYEVA Z.A., KHISOMOVA KH.K.
THE DEPARTMENT OF FAMILY MEDICINE TIPGPMP
Today viral infections are the leading cause of morbidity worldwide, the role of which in the overall morbidity will only increase. Recently in the treatment of viral infections extensive use of immunomodulators, the range is constantly expanding. The most promising drugs in the given as¬pect are interferon inducers. The article presents the results of studies of prophylactic effectiveness and treatment of acute respiratory viral infections interferon inducers of 150 patients aged from 1 month to 17 years. The results obtained showed that anaferon having a pronounced curative and prophylactic efficiency of the flu, when before vaccine period increases the functional activity of specific antibodies that reduce the intensity of morbidity. The ability of the drug to reduce the number of bacterial complications allowed authors to effectively apply anaferon in the treatment of viral infections in children with secondary immunodeficiency condition. The inclusion of anaferon in the standard therapy of acute intestinal virus infection in children significantly reduced the duration of the main symptoms of the disease. -
THE SYNDROME OF ENDOGENOUS INTOXICATION IN PATIENTS WITH CANCER OF THE MAMMARY GLAND
RASULOV S.R., MURODOV А.М., KHAMIDOV А.К., ASHUROVA M.J.
In the structure of the morbidity and mortality of the female population of cancer of the mammary gland takes the first place. The severity of manifestations of GIS in patients with cancer of the mammary gland caused by the passage of the disease (depending on the stage of the disease) and the applied method of special treatment: surgery, chemotherapy, radiation therapy. Study of biochemical markers of endogenous intoxication in patients with cancer of the mammary gland showed a decrease in total protein, albumin fraction and test the Paramecium, a slight increase in globulin, which testifies to the existence of the phenomena of intoxication depend on the stage of the prevalence of tumor process. In patients with cancer of the mammary gland, compared with healthy, have lower indicators of the quality of life, especially for the account of such scales as physical functioning and men-tal and emotional state. -
The complex of multifunctional solution reosorbilakt in intensive therapy with endogenous intoxication in patients with acute peritonitis.
Khamidov D.B. , Kosimov Z.K. , Khаmidov D.D., Kiyamоv S.E.
In 67 patients with acute peritonitis studied the degree of endogenous intoxication. The efficiency of complex polyfunctional solution reosorbilakt included in the program of infusion therapy for correction of endogenous intoxication in patients with acute peritonitis
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The organization and activity of diagnostic service of the various countries (the literature review)
Thus, the literature review has shown that diagnostics as scientific discipline, developed in indissoluble communication with other scientific disciplines. The key moment of its development was the wide experience of great scientific Gippokrata, Galena, Avitsenny, and also the organization of school of medicine in the countries of the East, Asia, Europe. Formation of the diagnostic centers, as in Europe, America, and in the countries of the former USSR became an important stage of development of diagnostic service. Activity of the kliniko-diagnostic centers shows their conclusive advantage and rather considerable role in public health services system. Thus efficiency of activity providing at the expense of introduction of the expensive equipment, modern methods of research and presence of highly-skilled personnel.
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THE ROLE OF FAMILY DOCTORS IN PLANNING FAMILY
MIRZOEVA Z.A., HISOMOVA H.K., ORTIKOVA M.M.
In the result of increasing level coverage of contraceptive methods decreasing the rate of birth, prevention of pregnancy, decreasing of abortion and chronic urogenital disease, decreasing of maternal mortality. -
THE IMPACT OF INDIRECT ELECTROCHEMICAL OXIDATION THE TOXICITY OF BLOOD IN PATIENTS IN THE TERMINAL PHASE OF PERITONITIS, DUE TO PANCREONECROSIS
DOSTIEVA Z.A., SHUMILINA O.V., MURADOV A.M., HAMROKULOV A.A.
THE DEPARTMENT OF EFFERENT MEDICINE AND INTENSIVE THERAPY TIPGPMP
In 15 patients with pancreonecrosis complicated by the terminal phase of peritonitis, we estimated the effect of indirect electrochemical blood oxidation on the state of the detoxification function of the lungs by intravenous 0,06% solution of sodium hypochlorite. To study the detoxification function of the lungs compared the blood of the right ventricle of the heart and arterial blood from radiotherapy or femoral artery, taken simultaneously. Study was carried out after 1 and 4-6 h after infusions of the mentioned solution. If, prior to the infusion of sodium hypochlorite concentration of urea and creatinine in the blood drains were reliably higher than in streams to the light respectively by 20,9% and 12,9%, for 1 hour, these figures are reduced to the respective indicators of 18,2% and 7,6%, and after 6 hours of light to see themselves their detoxifying that points to the restoration of detoxification functions of the body. The results obtained showed that sodium hypochlorite solution is a powerful oxidant toxic blood components, primarily amphiphilic, hydrophilic and hydrophobic metabolites, are in low – small and medium molecular fractions, as well as lipid structures of cell membranes due to changes in their perme¬ability and mode of operation. The use of a solution in the first 4-6 hours causes significant improvement detoxification function of the lungs and its recovery depending on the stage of the infringement. -
CRITERIONS OF CHOICE OF LAPAROSCOPIC CHOLECYSTECTOMY IN PERSONS OF OLDER AGE GROUPS
Aim. Determine criterions of choose of anesthetic maintenance and laparoscopic cholecystectomy in older age groups.
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ETHICS COMMISSION IN THE FIELD OF ORGAN TRANSPLANTATION
ISMOILOV S.S., GULSHANOVA S.F.
STATE INSTITUTE “THE NATIONAL RESEARCH CENTER OF ORGAN TRANSPLANTATION AND HUMAN TISSUE” OF THE MINISTRY OF HEALTH AND SOCIAL PROTECTION OF POPULATION OF REPUBLIC OF TAJIKISTAN
The activity of the Ethics Committee Transplantology Service in the Republic of Tajikistan has started in 2009 and is operated on the base of the Ministry of Health and Social Protection of population of Republic of Tajikistan. Accordance with the criteria for a correct assessment of the specific problematic situations of modern medical practice based on the Constitution and laws of the Republic of Tajikistan, in 2009-2013 were examined 126 cases of trained pairs (donor-recipient) for related transplantation.
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